Prevention of hypoglycemia and hypoglycemic emergencies
>> Saturday, February 28, 2009
Hypoglycemic attack has always been considered as a medical emergency, if it is left untreated for sometime can lead to permanent brain damage due to poor supply of glucose to brain, this damage is generally irreversible. Thus a slight alertness can save a person and can decrease the mrorbidity and mortality from hypoglycemia. Emergency management of acute hypoglycemic attack has been mentioned here at Emergency management of hypoglycemic attack.
Hypoglycemia is preventable to some extent, there are certain dietary modification and drug supplements which can prevent this. Hypoglycemia can occur as reactive or fasting as in case of insulinoma etc. Prevention in both the conditions are briefed below.
Prevention of reactive hypoglycemia
Reactive hypoglycemia can be prevented by simple modification of diet and some drugs which act to delay absorption of glucose leading to supplement glucose to blood.
Prevention of hypoglycemia by diet
A simple diatary manipulation and modification can prevent reactive hypoglycemia. A high protein diet is adviced because amino acid is a antitrigger factor and stimulate insulin release to a lesser extent than glucose. Thus a decreased intake of sugar containing foods, more protein diet and restricted calories are helpful to prevent hypoglycemia.
Prevention of hypoglycemia by drugs
There are certain drugs used in different conditions to prevent hypoglycemia. These are-
Anticholinergic drugs are used in prevention of hypoglycemia as they inhibit vgal action and delay gastric emptying in patients with accelerated glucose absorption.
Mild use of tranquilizers like meprobamate, lonazepam or alprazolam and avoidance of caffiene and cigarette smoking in anxious and hyperkinetic patient may be beneficial in preventing them from hypoglycemia.
Phenformin hydrochloride alleviate hypoglycemia in diabetes by inhibiting intestinal glucose absorption which in turninhibit insulin release.
Though not thoroughly evaluated but there are certain insulin inhibitors which has been used in prevention and treatment of hypoglycemia, these are diazoxides, phenytoin and propranolol (inderal).
In patients associated with early onset diabetes, the oral hypoglycemics sulfonylurea has been beneficial in preventing hypoglycemia in them because they restore sensitivity of beta cells to any kind of physiological stimulus.
Prevention of fasting hypoglycemia
Fasting hypoglycemia can occur in certain conditions like insulinoma and tumors of pancreas where there is excess insulin. Prevention of hypoglycemia can be done in these cases by
Surgery for prevention of hypoglycemia
In tumors like insulinomas it is recommended a surgical resection of functioning islet cell tumor in order to prevent hypoglycemia.
In some non resectable tumors of pancreas streptozocin is used. This streptozocin selectively destroys pancreatic tissues. However following this patient require life long insulin therapy.
These are some of the methods to prevent hypoglycemia in the conditions like tumors or as a complication of diabetes. A little consciousness and alertness can prevent this deadly complication. Read more...



